Leather and vinyl chairs are far easier to wipe clean with a mild detergent. If germs are a major concern, it is hard to beat the benefits of a smooth surface. Leather is more durable than vinyl but overall, they both work well. However, the downside is they tend to be more expensive and can be a little cold at first when you sit. Which is best for a particular individual is a judgement call based on personal preference.
MPN: HOD141$8.86 / EA
MPN: MIIPRM21408C$4.1 / PK
MPN: LLR60923$1070.1 / EA
MPN: STCS45PATCH6BL$7.15 / EA
MPN: CNMCLI221BK$19.86 / EA
MPN: ICX90780458$4.62 / PK
MPN: DVO94039110$89.61 / CT
MPN: UBR6601U0112$22.03 / PK
MPN: DIA35432$6.55 / EA
MPN: STCN6PATCH5YL$7.03 / EA
MPN: KFI2300BEAM3P3$946.99 / EA
MPN: SJMT1750TBKCT$244.81 / CT