Leather and vinyl chairs are far easier to wipe clean with a mild detergent. If germs are a major concern, it is hard to beat the benefits of a smooth surface. Leather is more durable than vinyl but overall, they both work well. However, the downside is they tend to be more expensive and can be a little cold at first when you sit. Which is best for a particular individual is a judgement call based on personal preference.
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MPN: VER99828$80.19 / EA
MPN: PAC5114$18.3 / PK
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MPN: CNMICMF462DW$381.63 / EA
MPN: PGC81216$20.91 / BX
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MPN: PNTPEN12185$5.97 / PK
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MPN: BBNEVNSL6490015$9.26 / EA