Leather and vinyl chairs are far easier to wipe clean with a mild detergent. If germs are a major concern, it is hard to beat the benefits of a smooth surface. Leather is more durable than vinyl but overall, they both work well. However, the downside is they tend to be more expensive and can be a little cold at first when you sit. Which is best for a particular individual is a judgement call based on personal preference.
MPN: KFI42R922SL38LE$566.75 / EA
MPN: GNMSN31849$58.45 / BX
MPN: SBK12411949$30.42 / EA
MPN: FCIFA100644FS$481.11 / EA
MPN: KFIBR2700P45$283.7 / EA
MPN: AVE05429$178.3 / CT
MPN: MMM655RPA$13.64 / PK
MPN: RAC91109$9.85 / PK
MPN: EUT801135$477.4 / EA
MPN: PGC15703$24.64 / CT
MPN: KCC09996$114.75 / EA
MPN: UNV10204$18.45 / BX